OA 30 or 60 mg once daily. Not to exceed 60 mg daily. RA &AS 60 mg once daily, may be increased to max: 90 mg once daily. Acute pain & gouty arthritis, primary dysmenorrhea Not to exceed 120 mg once daily for 8 days. Minor dental procedures Not to exceed 90 mg once daily for 8 days.
Discontinue use if hypersensitivity occurs. Not a substitute for aspirin in CV prophylaxis. Increased risk of thrombotic events eg, MI, stroke. Significant risk factors for CV events eg, HTN, hyperlipidaemia, DM, smoking. Hepatic or renal dysfunction. Not recommended in women of childbearing potential. Not to be used during pregnancy & lactation. Not to be given in childn. Elderly >65 yr.
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